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Article title

Contrast-phase Imaging of Fixed-Cells through Micro-Cavity Scanning Microscopy


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Contrast phase imaging at infrared wavelengths
is achieved through an extrinsic Fabry-Perot cavity in optical
fiber. The micro-cavity is realized by approaching a
cleaved fiber to a distance of about few tens of microns
from the surface under test. The probe is a single mode
fiber and is fed by a low-coherence source. The information
is extracted from the reflected spectrum, that starts
to be modulated by the interference when the fiber begins
to interact with the sample. The measurement of the
reflected optical intensity provides a map of the sample
reflectivity, whereas from the analysis of the spectrum in
the time/spatial domain, it is possible to extract topography
and refractive index variations. This information is
entangled in the contrast phase image obtained. In this
work we review the system proposed in [19] in order to
extract topography and local surface permittivity of biological
samples. The system displays tridimensional images
with a transverse resolution that is not limited by
the numerical aperture NA of the scanning probe (as suggested
by the Rayleigh limit), but it is related to the transverse
field behavior of the electromagnetic field inside the
micro-cavity. Differently, the source bandwidth, demodulation
algorithm and optical spectrum analyzer resolution
affect the resolution in the normal direction.







Physical description


11 - 9 - 2013
27 - 2 - 2014
9 - 5 - 2013


  • Dipartimento di Ingegneria
    dell’Informazione, Università Politecnica delle Marche,
    Ancona, 60131, Italy
  • Dept. of Neuroscience and Imaging, Università “G.
    d’Annunzio’, Via dei Vestini, 66013, Chieti Italy
  • Dip. di Scienze Chimiche e Farmaceutiche, Università di
    Trieste,Via Valerio, 34127, Trieste
  • Dipartimento di Ingegneria
    dell’Informazione, Università Politecnica delle Marche,
    Ancona, 60131, Italy
  • Dipartimento di Ingegneria
    dell’Informazione, Università Politecnica delle Marche,
    Ancona, 60131, Italy


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