Narrowly Dispersed Molecularly Imprinted Polymer Microspheres with Photo- and Thermo-Responsive Template Binding Properties in Pure Aqueous Media by RAFT Polymerization

• Authors: Yue Ma , Ying Zhang , Man Zhao , Xianzhi Guo , Huiqi Zhang
• Languages of publication: EN

Abstracts

EN

The facile and controlled synthesis of narrowly dispersed molecularly imprinted polymer (MIP) microspheres with both photo- and thermo-responsive template binding properties in pure aqueous media is described. Narrowly dispersed "living" core polymer microspheres with surface-immobilized dithioester groups were firstly prepared via reversible addition-fragmentation chain transfer (RAFT) precipitation polymerization (RAFTPP). The polymer microspheres were then successively grafted with an azobenzene (azo)-containing MIP layer and thermo-responsive poly(N-isopropylacrylamide) (PNIPAAm) brushes via surface-initiated RAFT polymerization to provide the desired product. The successful grafting of the azo-containing MIP layer and PNIPAAm brushes was confirmed by Fourier transform infrared (FT-IR) spectroscopy, scanning electron microscopy (SEM), and static contact angle experiments. The attachment of an azo-containing MIP layer onto the "living" core polymer beads with a narrow size distribution allows the direct generation of narrowly dispersed photoresponsive core-shell MIP microspheres. Moreover, the introduction of PNIPAAm brushes onto the core-shell MIP microspheres has been shown to significantly improve their surface hydrophilicity leading to pure water-compatibility. Additionally, this modification confers thermo-responsive template binding properties upon the microspheres.

Keywords

EN

Molecular imprinting; Polymer microspheres; Water-compatible; Photoresponsive; Thermo-responsive; RAFT polymerization

• Publisher: De Gruyter Open
• Journal: Molecular Imprinting
• Year: 2012
• Volume: 1
• Pages: 3-16

Dates

published

1 - 1 - 2012

accepted

13 - 6 - 2012

received

19 - 4 - 2012

online

2 - 7 - 2012

Contributors

author

Yue Ma

• Key Laboratory of Functional Polymer Materials (Nankai University), Ministry of Education, Department of Chemistry, Nankai University, Tianjin 300071, People's Republic of China

author

Ying Zhang

• Key Laboratory of Functional Polymer Materials (Nankai University), Ministry of Education, Department of Chemistry, Nankai University, Tianjin 300071, People's Republic of China

author

Man Zhao

• Key Laboratory of Functional Polymer Materials (Nankai University), Ministry of Education, Department of Chemistry, Nankai University, Tianjin 300071, People's Republic of China

author

Xianzhi Guo

• Key Laboratory of Functional Polymer Materials (Nankai University), Ministry of Education, Department of Chemistry, Nankai University, Tianjin 300071, People's Republic of China

author

Huiqi Zhang

• Key Laboratory of Functional Polymer Materials (Nankai University), Ministry of Education, Department of Chemistry, Nankai University, Tianjin 300071, People's Republic of China

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Identifiers

DOI

10.2478/molim-2012-0002