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2014 | 1 | 1 |

Article title

microRNA-based diagnostic and therapeutic
opportunities in lung cancer


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microRNAs (miRNAs) are a class of non-coding
RNA which suppress target gene expression. miRNAs are
involved in most physiological and pathological process,
including carcinogenesis. miRNA expression profiles help to
improve lung cancer diagnosis, classification and prognostic
information. Tumor suppressive and oncogenic miRNAs have
been discovered and their functions have been investigated.
Emphasis is placed on the development of miRNA-based
methods for lung cancer diagnosis and therapy and future
directions are proposed.







Physical description


12 - 4 - 2014
23 - 11 - 2014
29 - 4 - 2015


  • Laboratory of Metabolism, Center for Cancer
    Research, National Cancer Institute, National Institutes of Health,
    Bethesda, MD 20892, USA
  • Laboratory of Metabolism, Center for Cancer
    Research, National Cancer Institute, National Institutes of Health,
    Bethesda, MD 20892, USA
  • Department of Thoracic and Head&Neck
    Medical Oncology, University of Texas MD Anderson Cancer Center,
    Houston, TX 77030, USA


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