Role of miR-200a in regulating the insulin signalling in the hypothalamus

• Authors: Poonam Pandey , Vasudevan Seshadri
• Languages of publication: EN

Keywords

EN

miR-200a; Leptin; Insulin

• Publisher: De Gruyter Open
• Journal: Non-coding RNAs in Endocrinology
• Year: 2014
• Volume: 1
• Issue: 1

Dates

received

1 - 4 - 2014

online

19 - 9 - 2014

accepted

4 - 7 - 2014

Contributors

author

Poonam Pandey

• National Centre for Cell Science, Pune, Maharashtra, India

author

Vasudevan Seshadri

• National Centre for Cell Science, Pune, Maharashtra, India

References

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• [2] Crepin D, Benomar Y, Riffault L et al. The over-expression of miR-200a in the hypothalamus of ob/ob mice is linked to leptin and insulin signaling impairment. Mol Cell Endocrinol 2014;384(1-2):1-11.[WoS]
• [3] Sangiao-Alvarellos S, Pena-Bello L, Manfredi-Lozano M et al. Perturbation of Hypothalamic MicroRNA Expression Patterns in Male Rats After Metabolic Distress: Impact of Obesity and Conditions of Negative Energy Balance. Endocrinology 2014;155(5):1838-50.
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• [8] Kleinridders A, Lauritzen HP, Ussar S et al. Leptin regulation of Hsp60 impacts hypothalamic insulin signaling. J Clin Invest 2013;123(11):4667-80.
• [9] Magenta A, Cencioni C, Fasanaro P et al. miR-200c is upregulated by oxidative stress and induces endothelial cell apoptosis and senescence via ZEB1 inhibition. Cell Death Differ 2011;18(10):1628-39.[WoS]
• [10] Burk U, Schubert J, Wellner U et al. A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells. EMBO Rep 2008;9(6):582-9.[WoS]
• [11] Saykally JN, Dogan S, Cleary MP et al. The ZEB1 transcription factor is a novel repressor of adiposity in female mice. PLoS One 2009;4(12):e8460.[WoS][Crossref]
• [12] Feng X, Wang Z, Fillmore R et al. MiR-200, a new star miRNA in human cancer. Cancer Lett 2014;344(2):166-73.
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Identifiers

DOI

10.2478/micrnado-2014-0003