Diversity oriented, efficient and sustainable synthetic protocol for the synthesis of structurally diverse drug-like complex heterocycles, incorporating privileged heterocyclic systems

• Authors: Sarita Khandelwal , Anshu Rajawat , Yogesh Kumar Tailor , Hemant Kumar Jain , Mahendra Kumar
• Languages of publication: EN

Abstracts

EN

A diversity oriented, efficient and sustainable
synthetic protocol has been presented for the synthesis
of structurally diverse drug-like small heterocycles
with structural complexity. The present synthetic
strategy involves a three-component domino reaction of
2-aminobenzothiazoles, thiophene-2-carbaldehyde and
carbonyl compounds in the presence of a catalytic amount
of sulfamic acid as a recyclable ecofriendly acid catalyst.

Keywords

EN

2-Aminobenzothiazoles; Benzothiazoloquinazolinones; Benzo[h]benzothiazoloquinazolines; Diversity oriented synthesis; Multicomponent reactions; Quinazolinones

• Publisher: De Gruyter Open
• Journal: Diversity Oriented Synthesis
• Year: 2012
• Volume: 1
• Issue: 1

Dates

accepted

1 - 9 - 2014

received

14 - 7 - 2014

online

19 - 9 - 2014

Contributors

author

Sarita Khandelwal

• Department of Chemistry, University of Rajasthan, Jaipur, 302004, India

author

Anshu Rajawat

• Department of Chemistry, University of Rajasthan, Jaipur, 302004, India

author

Yogesh Kumar Tailor

• Department of Chemistry, University of Rajasthan, Jaipur, 302004, India

author

Hemant Kumar Jain

• Department of Chemistry, University of Rajasthan, Jaipur, 302004, India

author

Mahendra Kumar

• Department of Chemistry, University of Rajasthan, Jaipur, 302004, India

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Identifiers

DOI

10.2478/dos-2014-0002