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2014 | 27 | 1 | 55-60

Article title

In vitro evaluation of immunogenic properties of active dressings


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The aim of this study was in vitro evaluation of the level of the immune response in relation to wound dressings composed of alginate, calcium carboxymethylcellulose, and dibutyrylochitin and determination of the direction of response, which will make referring next to the results of in vivo phase possible. The subject of the experiments was to examine the commercially available, biodegradable alginate dressing, commercially available but not biodegradable dressing constructed from the sodium carboxymethylcellulose, and synthesized in house biodegradable dressing constructed of the dibutyrylchitin. To determine the direction of the immune response, the degree of secretion of pro-inflammatory interleukin (IL-1, IL-6) and antiinflammatory (IL-10) interleukin from murine fibroblasts having contact with the tested dressings (ELISA enzyme linked immunosorbent assay), was tested.










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1 - 6 - 2014
10 - 3 - 2014
20 - 2 - 2014
30 - 5 - 2014


  • Ph.D. Student, Medical University of Lodz, Pl. Hallera 1, 90-647 Lodz, Poland
  • Science and Research Laboratory Dermin Sp. z o.o., Milionowa 23, 93-193 Lodz, Po
  • Department of Biopharmaceutics, Medical University of Lodz, Muszynskiego 1, 90-153 Lodz, Poland
  • Science and Research Laboratory Dermin Sp. z o.o., Milionowa 23, 93-193 Lodz, Po
  • Science and Research Laboratory Dermin Sp. z o.o., Milionowa 23, 93-193 Lodz, Po
  • Department of Biopharmaceutics, Medical University of Lodz, Muszynskiego 1, 90-153 Lodz, Poland


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