FAPA mass spectrometry of hydroxychalcones. Comparative studies with classical methods of ionization

• Authors: Marek Smoluch , Grazyna Bartkowiak , Edward Reszke , Wojciech Lechowicz , Jerzy Silberring , Grzegorz Schroeder
• Languages of publication: EN

Abstracts

EN

In this paper we are focused on analysis of hydroxychalcones, i.e. 2’-hydroxychalcone, 3’-hydroxychalcone and 4’-hydroxychalcone, by the Flowing Atmospheric Pressure Afterglow mass spectrometry (FAPA-MS), and on comparison of the obtained data with other classical methods including ESI-MS, APCI, MALDI, and GC/EI-MS. The paper is presenting fragmentation pathways of both positive-, and negative hydroxychalcone ions. Tested compounds were characterized by comparison of the results (signals m/z and relative intensities) from the five mass spectrometry techniques, showing very good utility of FAPA method for fast and easy analysis of the low molecular weight compounds. Moreover, FAPA does not require a time-consuming derivatization, nor search for a suitable solvent or matrix, often incompatible with various ion sources.

Keywords

EN

FAPA; mass spectrometry; hydroxychalcones

• Publisher: De Gruyter Open
• Journal: Current Issues in Pharmacy and Medical Sciences
• Year: 2014
• Volume: 27
• Issue: 1
• Pages: 27-31

Dates

published

1 - 6 - 2014

received

13 - 2 - 2014

online

30 - 5 - 2014

accepted

7 - 3 - 2014

Contributors

author

Marek Smoluch

• AGH University of Science and Technology, Department of Biochemistry and Neurobiology, Faculty of Materials Science and Ceramics, Mickiewicza 30, 30-059 Cracow, Poland

author

Grazyna Bartkowiak

• Adam Mickiewicz University in Poznań, Faculty of Chemistry, Umultowska 89b, 61-614 Poznan, Poland

author

Edward Reszke

• ERTEC-Poland, Rogowska 146/5, 54-440 Wroclaw, Poland

author

Wojciech Lechowicz

• Institute of Forensic Research, Westerplatte 9, 31-033 Cracow, Poland

author

Jerzy Silberring

• AGH University of Science and Technology, Department of Biochemistry and Neurobiology, Faculty of Materials Science and Ceramics, Mickiewicza 30, 30-059 Cracow, Poland
• Centre of Polymer and Carbon Materials, Polish Academy of Sciences, Curie-Sklodowskiej 34, 41-819 Zabrze, Poland

author

Grzegorz Schroeder

• Adam Mickiewicz University in Poznań, Faculty of Chemistry, Umultowska 89b, 61-614 Poznan, Poland

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Identifiers

DOI

10.2478/cipms-2014-0008