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Article title

Bio-effects Monitoring of Workers in the Cotton Industry


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There is still unprotected and continuous
exposure to cotton dusts, endotoxins, chemicals due to
chemical and mechanical processes and to ergonomic
hazards in the cotton industry of Pakistan, resulting
in different types of public health problems in cotton
workers. The aim of the study is to determine the
prevalence of byssinosis and other public health problems
in cotton factories of Faisalabad; to measure cotton
dusts and endotoxins in different cotton factories and to
correlate their effects on lungs via Pulmonary Function
Tests (PFTs) and to determine cytotoxic and genotoxic
cellular effects in buccal cells due to long term exposure
to cotton dusts and endotoxins in exposed cotton workers
against a controlled/non-exposed group. Public health
problems and occupational safety will be assessed via
a structured check list. A structured questionnaire will
be administered to 800 cotton workers to determine the
prevalence of byssinosis and other health problems. PFTs
will be performed on selected exposed cotton workers.
Cotton dusts and endotoxins will be measured in different
sections of different cotton factories. Buccal cells will be
collected from 50 exposed cotton weavers and also from
similar numbered matched controlled/non-exposed
group. The organic cotton dusts contain endotoxin which
is associated with acute and chronic inflammation of the
respiratory tract, resulting in decline in lung function
and in a clinical condition called “byssinosis”, organic
dust toxic syndrome and chronic airway obstruction.
As the exposure leads to inflammation, so there may be
cytotoxicity in buccal cells.








Physical description


23 - 4 - 2014
23 - 5 - 2014
4 - 7 - 2014


  • Institute of Environmental
    Hygiene, Center for Public Health, Medical University of Vienna,
    1090 Vienna, Austria; Federal Government Polyclinic (PGMI), Islamabad,
  • Institute of Cancer Research, Department of
    Medicine I, Comprehensive Cancer Center, Medical University of
    Vienna, 1090 Vienna, Austria


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