Structural factors influencing the reaction rates of 4-aryloxy-7-nitrobenzofurazans with amino acids

• Authors: Marioara Bem , Marilena Vasilescu , Miron Caproiu , Constantin Draghici , Adrian Beteringhe , Titus Constantinescu , Mircea Banciu , Alexandru Balaban
• Languages of publication: EN

Abstracts

EN

An interesting observation was made when studying the SNAr reaction between several 4-aryloxy-7-nitrobenzofurazans (2) and several amino acids leading to the apparition of detectable fluorescence from the substitution products3. Acidic amino acids reacted very slowly=while basic amino acids react fastest with2 having an unsubstituted phenyl or a 4-formyl-phenyl Ar group. Amongst neutral amino acids, proline reacts fastest at room temperature after 100 min. With2 having a methoxy-subtituted Ar group.

Keywords

EN

4-Aryloxy-7-nitrobenzofurazans; amino acids; SNAr reaction; fluorescence

• Publisher: De Gruyter Open
• Journal: Open Chemistry
• Year: 2004
• Volume: 2
• Issue: 4
• Pages: 672-685

Dates

published

1 - 12 - 2004

online

1 - 12 - 2004

Contributors

author

Marioara Bem

• Laboratory of Supramolecular Chemistry and Interphase Processes, Institute “I.G. Murgulescu” of Physical Chemistry of Roumanian Academy, Splaiul Independentei 202, 77208, Bucharest, Roumania

author

Marilena Vasilescu

• Structure Laboratory, Institute “I.G. Murgulescu” of Physical Chemistry of Roumanian Academy, Splaiul Independentei 202, 77208, Bucharest, Roumania

author

Miron Caproiu

• Institute “C.D. Nenitzescu” of Organic Chemistry, Romanian Academy, Splaiul Independentei 202 B, Bucharest, Roumania

author

Constantin Draghici

• Institute “C.D. Nenitzescu” of Organic Chemistry, Romanian Academy, Splaiul Independentei 202 B, Bucharest, Roumania

author

Adrian Beteringhe

• Laboratory of Supramolecular Chemistry and Interphase Processes, Institute “I.G. Murgulescu” of Physical Chemistry of Roumanian Academy, Splaiul Independentei 202, 77208, Bucharest, Roumania

author

Titus Constantinescu

• Laboratory of Supramolecular Chemistry and Interphase Processes, Institute “I.G. Murgulescu” of Physical Chemistry of Roumanian Academy, Splaiul Independentei 202, 77208, Bucharest, Roumania

author

Mircea Banciu

• Department of Organic Chemistry, “Politehnica” University Bucharest, Splaiul Independentei 313, Bucharest, Roumania

author

Alexandru Balaban

• Department of Marine Sciences, Texas A & M University at Galveston, 5007 Ave. U, 77553-1675, Galveston, TX, USA

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Identifiers

DOI

10.2478/BF02482730