Two new computer diagnostic methods for the automatic determination of glaucoma diagnosis are presented and compared in this paper: the statistical method and the neural net method. Both introduced methods evaluate colour glaucomatous changes within the optic disc area. The mentioned colour changes are numerically represented using a suitable image analysis process. Next, the investigated eye is classified to three defined glaucoma-risk classes with different reliability of the diagnosis determination. The verification and the reliability comparison of both studied methods are performed by virtue of the application of this methods to a set of normal healthy optic disc images and a set of glaucomatous optic disc images.