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2015 | 52 | 3 | 71-73
Article title

Autophagy - Adaptive Molecular Mechanisms in Condition of Starvation

Content
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Languages of publication
EN
Abstracts
EN
Autophagy is an extremely old process during which long-lived proteins and cellular organelles are removed by means of lysosomes. Autophagy may be caused by cellular stress mechanisms. Research has proven that autophagy plays a key role in obtaining nutrients and adapting to the conditions of starvation. Owing to this, it takes part in maintaining homeostasis in cytoplasm and cell nucleus. This objective may be achieved through a number of ways. Depending on the manner in which a substrate connects with the lysosome, we can talk about macroautophagy and microautophagy. Additionally, some authors also distinguish a chaperone-mediated autophagy. The article presented below describes molecular mechanisms of each type of autophagy and focuses particularly on macroautophagy, which is the best understood of all the autophagy types.
Publisher
Year
Volume
52
Issue
3
Pages
71-73
Physical description
Dates
published
1 - 9 - 2015
accepted
20 - 7 - 2015
online
30 - 12 - 2015
received
5 - 6 - 2015
References
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Document Type
Publication order reference
YADDA identifier
bwmeta1.element.-psjd-doi-10_1515_phr-2015-0018
Identifiers
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