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Journal
2015 | 2 | 1 |
Article title

Unravelling peptidomes by in silico mining

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EN
Abstracts
EN
Peptides of great number and diversity occur in
all domains of life and exhibit a range of pharmaceutically
relevant bioactivities. The complexity of biological
samples including human cells or tissues, plant extracts
or animal venom cocktails, often impedes the discovery
of novel bioactive peptides using mass spectrometrybased
peptidomics analysis. An increasing number of
publicly available genome and transcriptome datasets,
together with refined bioinformatics analysis, allows for
rapid identification of novel peptides which may have
been previously unrecognized. Moreover, a combination
of information extracted from in silico mining approaches
together with data derived from mass spectrometrybased
studies provides new impetus for future peptidome
analyses, including the discovery of novel bioactive
peptides that can serve as starting points for drug
development.
Publisher
Journal
Year
Volume
2
Issue
1
Physical description
Dates
received
1 - 12 - 2014
accepted
11 - 2 - 2015
online
31 - 3 - 2015
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Document Type
Publication order reference
YADDA identifier
bwmeta1.element.-psjd-doi-10_1515_ped-2015-0002
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