Retrospective analysis of prenatal echcardiography findings in cases of congenital heart defects: comparison with postnatal pulmonary hypertension revealed by lungs histopathology (2010-2015)

• Authors: Hanna Romanowicz , Ewa Czichos , Katarzyna Zych-Krekora , Michał Krekora , Maciej Słodki , Maria Respondek-Liberska
• Languages of publication: EN

Abstracts

EN

Introduction:It was retrospective analysis of prenatal echocardiography findings in fetuses with congenital heart defects, who died in our institution and had an autopsy exams in years 2010 - 2015. Material and methods:Among total 115 deaths the pulmonary hypertension based on histopathology criteria was present in 83 cases (72%) as a leading cause of their deaths. Out of 83 neonates 40 underwent prenatal echo, 43 did not, however in both groups there were similar types of heart defects. Results:The prenatal echo findings from study group (n=40), from the last echo before the delivery were compared with control group and group of HLHS who did survive neonatal surgery and were discharged from hospital. There were statistical differences between pulmonary artery/aorta ratio in fetuses in control group and fetuses in study group („pulmonary hypertension” after birth) (p=0,044). There were statistical differences between pre-delivery pulmonary artery/aorta ratio in fetuses in study group (with „pulmonary hypertension” after birth) and in group of fetuses with HLHS, alive & well after first surgery (p=0,027). There were no differences between pulmonary artery/ aorta ratio fetuses in control group and fetuses with HLHS, alive & well after first surgery (p=0,38) Conclusion: 1) Pulmonary hypertension was a frequent cause of neonatal deaths among our series of congenital heart defects 2) Dilatation of pulmonary artery (and increased pulmonary/artery ratio ) in fetal echo just before delivery may be an important risk factor for poor neonatal outcome in congenital heart defects.)

Keywords

EN

fetal echo; pulmonary artery; pulmonary hypertension after delivery; autopsy

• Publisher: De Gruyter Open
• Journal: Prenatal Cardiology
• Year: 2015
• Volume: 5
• Issue: 4
• Pages: 12-18

Dates

published

1 - 12 - 2015

received

1 - 9 - 2015

accepted

22 - 12 - 2015

online

5 - 3 - 2016

Contributors

author

Hanna Romanowicz

• Department of Pathology Polish Mother’s Memorial Hospital, Research Institute

author

Ewa Czichos

• Department of Pathology Polish Mother’s Memorial Hospital, Research Institute

author

Katarzyna Zych-Krekora

• Department of Prenatal Cardiology, Polish Mother’s Memorial Hospital, Research Institute

author

Michał Krekora

• Department of Obstetrics & Gynecology, Polish Mother’s Memorial Hospital, Research Institute

author

Maciej Słodki

• Department of Prenatal Cardiology, Polish Mother’s Memorial Hospital, Research Institute

author

Maria Respondek-Liberska

• Department of Prenatal Cardiology, Polish Mother’s Memorial Hospital, Research Institute
• Department for Fetal Malformations, Medical University of Lodz

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Identifiers

DOI

10.1515/pcard-2015-0002