Molecularly imprinted polymers (MIPs) are
synthetic receptors with tailor-made recognition sites for
the target molecules. Their high molecular recognition
ability, good stability, easy preparation, and low cost
make them highly promising substitutes for biological
receptors. Recent years have witnessed rapidly increasing
interest in the imprinting of biomacromolecules and
especially proteins because of the great potential of
these MIPs in such applications as proteome analysis,
clinical diagnostics, and biomedicine. So far, some
useful strategies have been developed for the imprinting
of proteins and controlled radical polymerization
techniques have proven highly versatile for such purpose.
This mini-review describes recent developments in the
controlled preparation of proteins-imprinted polymers
via such advanced polymerization techniques.