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Number of results
2014 | 2 | 1 |

Article title

Molecular imprinting in particle-stabilized
emulsions: enlarging template size from small
molecules to proteins and cells


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Molecular imprinting of small organic
compounds is now a standard procedure for preparation
of tailor-designed affinity materials. Molecularly
imprinted polymers (MIPs) have outstanding stability and
can be prepared in a large quantity, therefore are useful
replacements for biological receptors for a number of
applications including product purification, analytical
separation, chemical sensing and controlled delivery
and biomineralization. Although preparation of MIPs, in
particular using the non-covalent imprinting strategy, has
become a routine practice in many research laboratories,
new synthetic methods continued to be invented, which
contribute to new MIPs with unprecedented functional
performances. As the size of the template increases
from small organic compounds to biomacromolecules to
large virus particles and cells, the traditional methods of
imprinting often fail to give useful MIP products. Another
important aspect is the shift from organic solvents to
water for MIPs designed for treatment or analysis of
biological samples. The demand on water-compatibility
and recognition of larger entities for MIPs call for new
and efficient synthetic methods. This mini review will
summarize the recent progress of molecular imprinting
using particle-stabilized emulsion as a general synthetic
platform to furnish the new MIPs with the desired







Physical description


18 - 9 - 2015
26 - 6 - 2015
8 - 1 - 2016


  • Division of Pure and Applied
    Biochemistry, Department of Chemistry, Lund University, Box 124,
    221 00 Lund, Sweden
  • Division of Pure and Applied
    Biochemistry, Department of Chemistry, Lund University, Box 124,
    221 00 Lund, Sweden
  • School of Public Health, Tongji Medical College, Huazhong
    University of Science and Technology, Wuhan 430030, China


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