Our experience of liver Epithelioid
Hemangioendothelioma: from a misdiagnosis to
liver transplantation with long term follow-up

• Authors: Antonio Giuliani , Bruno Amato , Giuseppina Marino Marsilia , Domenico Tafuri , Antonio Ceriello , Walter Santaniello , Loredana Sodano , Aldo Rocca
• Languages of publication: EN

Abstracts

EN

Malignant Hepatic Epithelioid hemangioendothelioma
(HEHE) is an uncommon vascular tumor of intermediate
malignant potential. HEHE is a rare tumor and it
is difficult to diagnose for surgeons, hepatologists, radiologists
and pathologists. So, misdiagnosis with a delay
of the treatment is not uncommon.
We describe a case of a young woman with a diagnosis of
HEHE made 6 years after the first evidence of liver mass
with a very long term follow-up after surgical treatment.
She had two diagnoses of Hepatocellurar carcinoma (HCC)
and a diagnosis of Cholangiocarcinoma after three different
fine needle biopsies. After clinical observation, a new
laparoscopic core biopsy was performed. In a first time
approach, considering clinical and radiological patterns,
a diagnosis of Budd-Chiari Syndrome was finally made.
For that the patient underwent an orthotopicliver transplantation
(OLTx).
The surgical sample histological analysis allowed a definitive
diagnosis of HEHE. At last, at follow up 7 years after three OLTx the patient
is still alive and in good health with no evidence of
recurrence.

Keywords

EN

Hepatichemangioendothelioma; liver transplantation; laparoscopic liver surgery

• Publisher: De Gruyter Open
• Journal: Open Medicine
• Year: 2014
• Volume: 10
• Issue: 1

Dates

accepted

2 - 11 - 2015

online

21 - 12 - 2015

received

23 - 10 - 2015

Contributors

author

Antonio Giuliani

• Unit of Hepatobiliary Surgery and Liver Transplant Center,
  Department of Gastroenterology and Transplantation,”A. Cardarelli”
  Hospital, Naples, Italy

author

Bruno Amato

• Department of Clinical Medicine and Surgery, University
  of Naples Federico II, Italy

author

Giuseppina Marino Marsilia

• Department of Pathology, A. Cardarelli
  Hospital, Naples, Italy

author

Domenico Tafuri

• Department of Sport Sciences and Wellness, University
  of Naples “Parthenope”, Naples, Italy

author

Antonio Ceriello

• Unit of Hepatobiliary Surgery and Liver Transplant Center,
  Department of Gastroenterology and Transplantation,”A. Cardarelli”
  Hospital, Naples, Italy

author

Walter Santaniello

• Unit of Hepatobiliary Surgery and Liver Transplant Center,
  Department of Gastroenterology and Transplantation,”A. Cardarelli”
  Hospital, Naples, Italy

author

Loredana Sodano

• Unit of Hepatobiliary Surgery and Liver Transplant Center,
  Department of Gastroenterology and Transplantation,”A. Cardarelli”
  Hospital, Naples, Italy

author

Aldo Rocca

• Unit of Hepatobiliary Surgery and Liver Transplant Center,
  Department of Gastroenterology and Transplantation,”A. Cardarelli”
  Hospital, Naples, Italy

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Identifiers

DOI

10.1515/med-2015-0086