Research on the treatment of Pseudomonas aeruginosa pneumonia in children by macrolide antibiotics

• Authors: Xu-qiang Huang , Li Deng , Gen Lu , Chun-hui He , Pei-qiong Wu , Zhi-wei Xie , Muhammad Aqeel Ashraf
• Languages of publication: EN

Abstracts

EN

To observe a therapeutic effect of macrolide antibiotics in children with Pseudomonas aeruginosa pneumonia. Fifty-four cases of children with Pseudomonas aeruginosa pneumonia were randomly divided into an observation group (n=30) and a control group (n=24). The observation group was treated with macrolide antibiotics and cefoperazone/sulbactam. The control group was treated with cefoperazone/ sulbactam during a course of 10-14 days. The total effective rate was 93.3% in the observation group, and 58.3% in the control group, and results in the observation group were superior to the control group notably (P>0.05). There were no significant differences in bacterial clearance rate, adverse reaction rate between two groups (P>0.05). The combined application of cefoperazone/sulbactam with macrolide antibiotics to treat Pseudomonas aeruginosa pneumonia in children would be a more effective clinical method.

Keywords

EN

Pseudomonas Aeruginosa Pneumonia; Macrolide Antibiotics

• Publisher: De Gruyter Open
• Journal: Open Medicine
• Year: 2014
• Volume: 10
• Issue: 1

Dates

published

1 - 1 - 2015

received

10 - 7 - 2015

online

17 - 12 - 2015

accepted

9 - 11 - 2015

Contributors

author

Xu-qiang Huang

• Department of Respiration, Guangzhou Women and Children’s Medical Center, Guangzhou, 510120, China

author

Li Deng

• Department of Respiration, Guangzhou Women and Children’s Medical Center, Guangzhou, 510120, China

author

Gen Lu

• Department of Respiration, Guangzhou Women and Children’s Medical Center, Guangzhou, 510120, China

author

Chun-hui He

• Department of Respiration, Guangzhou Women and Children’s Medical Center, Guangzhou, 510120, China

author

Pei-qiong Wu

• Department of Respiration, Guangzhou Women and Children’s Medical Center, Guangzhou, 510120, China

author

Zhi-wei Xie

• Department of Respiration, Guangzhou Women and Children’s Medical Center, Guangzhou, 510120, China

author

Muhammad Aqeel Ashraf

• Faculty of Science & Natural Resources, Universiti Malaysia Sabah 88400 Kota Kinabalu Sabah Malaysia

References

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Identifiers

DOI

10.1515/med-2015-0082