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Journal
2014 | 10 | 1 |
Article title

Research on the treatment of Pseudomonas aeruginosa pneumonia in children by macrolide antibiotics

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EN
Abstracts
EN
To observe a therapeutic effect of macrolide antibiotics in children with Pseudomonas aeruginosa pneumonia. Fifty-four cases of children with Pseudomonas aeruginosa pneumonia were randomly divided into an observation group (n=30) and a control group (n=24). The observation group was treated with macrolide antibiotics and cefoperazone/sulbactam. The control group was treated with cefoperazone/ sulbactam during a course of 10-14 days. The total effective rate was 93.3% in the observation group, and 58.3% in the control group, and results in the observation group were superior to the control group notably (P>0.05). There were no significant differences in bacterial clearance rate, adverse reaction rate between two groups (P>0.05). The combined application of cefoperazone/sulbactam with macrolide antibiotics to treat Pseudomonas aeruginosa pneumonia in children would be a more effective clinical method.
Publisher
Journal
Year
Volume
10
Issue
1
Physical description
Dates
published
1 - 1 - 2015
received
10 - 7 - 2015
online
17 - 12 - 2015
accepted
9 - 11 - 2015
References
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  • [5] Demei Z., Fu W., Fupin H., et al., 2010 CHINET surveillance of bacterial resistance in China, Chinese Journal of Infection and Chemotherapy, 2011, 11(5), 321-329
  • [6] Robert A., Bonomo R.A., Szabo D., Mechanisms of multidrug resistance in Acinetobacter Species and Pseudomonas aeruginosa, Clin. Infect. Dis., 2006, 43, (2), S49-56
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  • [8] Chen X., Jin Y., Tang G., New pharmacology, Beijing, People’s Health Publishing House, 2011, 95-107
  • [9] Li H., Li H.P., The mechanism study progress for the macrolide drug treatment of diffuse pan-bronchiolitis, Journal of Clinical Internal Medicine, 2011, 28(7), 500-502
Document Type
Publication order reference
YADDA identifier
bwmeta1.element.-psjd-doi-10_1515_med-2015-0082
Identifiers
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