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Number of results

Journal

2014 | 10 | 1 |

Article title

Research on the treatment of Pseudomonas aeruginosa pneumonia in children by macrolide antibiotics

Content

Title variants

Languages of publication

EN

Abstracts

EN
To observe a therapeutic effect of macrolide antibiotics in children with Pseudomonas aeruginosa pneumonia. Fifty-four cases of children with Pseudomonas aeruginosa pneumonia were randomly divided into an observation group (n=30) and a control group (n=24). The observation group was treated with macrolide antibiotics and cefoperazone/sulbactam. The control group was treated with cefoperazone/ sulbactam during a course of 10-14 days. The total effective rate was 93.3% in the observation group, and 58.3% in the control group, and results in the observation group were superior to the control group notably (P>0.05). There were no significant differences in bacterial clearance rate, adverse reaction rate between two groups (P>0.05). The combined application of cefoperazone/sulbactam with macrolide antibiotics to treat Pseudomonas aeruginosa pneumonia in children would be a more effective clinical method.

Publisher

Journal

Year

Volume

10

Issue

1

Physical description

Dates

published
1 - 1 - 2015
received
10 - 7 - 2015
online
17 - 12 - 2015
accepted
9 - 11 - 2015

Contributors

  • Department of Respiration, Guangzhou Women and Children’s Medical Center, Guangzhou, 510120, China
author
  • Department of Respiration, Guangzhou Women and Children’s Medical Center, Guangzhou, 510120, China
author
  • Department of Respiration, Guangzhou Women and Children’s Medical Center, Guangzhou, 510120, China
author
  • Department of Respiration, Guangzhou Women and Children’s Medical Center, Guangzhou, 510120, China
author
  • Department of Respiration, Guangzhou Women and Children’s Medical Center, Guangzhou, 510120, China
author
  • Department of Respiration, Guangzhou Women and Children’s Medical Center, Guangzhou, 510120, China
  • Faculty of Science & Natural Resources, Universiti Malaysia Sabah 88400 Kota Kinabalu Sabah Malaysia

References

  • [1] Fujitani S., Sun H., Victor L., Pneumonia due to Pseudomonas aeruginosa, CHEST, 2011, 139(4), 909-919
  • [2] Fu W., Demei Z., Fupin H., et al., 2012 CHINET surveillance of bacterial resistance in China, Chinese Journal of Infection and Chemotherapy, 2013, 13(5), 321-330
  • [3] Hongbing C., Chunjiang Z., Hui W., et al., The common pathogens resistance analysis of nosocomial infections in 13 teaching hospitals in china in 2011, Chinese Journal of Internal Medicine, 2013, 52(3), 203-212
  • [4] Gaynes R., Edwards J.R., Overview of nosocomial infections caused by gram-negative bacilli, Clin. Infect. Dis., 2005, 41(6), 848-854[Crossref]
  • [5] Demei Z., Fu W., Fupin H., et al., 2010 CHINET surveillance of bacterial resistance in China, Chinese Journal of Infection and Chemotherapy, 2011, 11(5), 321-329
  • [6] Robert A., Bonomo R.A., Szabo D., Mechanisms of multidrug resistance in Acinetobacter Species and Pseudomonas aeruginosa, Clin. Infect. Dis., 2006, 43, (2), S49-56
  • [7] Ning F.G., Zhao X.Z., Bian J., et al., Large-area burns with pandrug- resistant Pseudomonas aeruginosa infection and respiratory failure, Chin. Med. J. (Engl)., 2011, 124(3), 359-363
  • [8] Chen X., Jin Y., Tang G., New pharmacology, Beijing, People’s Health Publishing House, 2011, 95-107
  • [9] Li H., Li H.P., The mechanism study progress for the macrolide drug treatment of diffuse pan-bronchiolitis, Journal of Clinical Internal Medicine, 2011, 28(7), 500-502

Document Type

Publication order reference

Identifiers

YADDA identifier

bwmeta1.element.-psjd-doi-10_1515_med-2015-0082
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