PL EN


Preferences help
enabled [disable] Abstract
Number of results
Journal
2014 | 10 | 1 |
Article title

Research into the Predictive Effect of TEG in the Changes of Coagulation Functions of the Patients with Traumatic Brain Hemorrhage

Content
Title variants
Languages of publication
EN
Abstracts
EN
To analyze the predictive effect of thrombelastogram (TEG) in the changes of coagulation functions of patients with traumatic brain hemorrhage, as well as to provide a practice basis for clinical guidance. 54 cases were observed from Aug. 2013–Oct. 2014. All patients received a TEG test 1d, 3d and 7d after traumatic injury. According to the statistical analysis, the comparison among the aforementioned coagulation function parameters in each group of patients, K, α and Ma all had significant differences. In the comparison between different time points in the same group, there was still a significant difference. Compared to the patients, the changes of R and K reached the lowest at 1d and the highest at 3d, but there was no significant difference between two groups at 7d. The changes of α and Ma reached its highest at 1d and the lowest at 3d after traumatic injury, but there was no significant difference at 7d. There was some difference in changes of coagulation functions between all groups. The former was more serious and the changes of coagulation functions had certain regularity, i.e., after traumatic injury, 1d showed a hypercoagulable state; 3d showed a hypocoagulable state; the coagulation functions of 7d returned to normal.
Publisher
Journal
Year
Volume
10
Issue
1
Physical description
Dates
published
1 - 1 - 2015
accepted
15 - 10 - 2015
online
17 - 12 - 2015
received
29 - 6 - 2015
References
  • [1] Cai Haiying; Study of the application value of thrombelastogram in multiple-trauma patients [D]; Zhejiang Univertsity; 2010.
  • [2] Zhang Bing; Relation between coagulation disorder dysfunction and thrombelastogram and severity and prognosis of septicopyemia [D]; Shanxi Medical University; 2013.
  • [3] Nekludov M., Bellander B.M., Blomback M., et al., Platelet dysfunction in patients with severe traumatic brain injury, J. Journal of Neurotrauma, 2007, 24(11), 1699-1706[Crossref][WoS]
  • [4] Yan Z., Application of thrombelastogram in severe thrombocytopenia patients, D. Chongqing Medical University, 2011
  • [5] Finfer S.R., Cohen J., severe traumatic brain injury, J. Resuscitation, 2001, 48(1), 77-90[Crossref]
  • [6] Giacino J.T., Whyte J., Bagiella E., et al., Placebo-controlled trial of amantadine for severe traumatic brain injury, J. New England Journal of Medicine, 2012, 366(9) 819-826[WoS]
  • [7] Xinghua P., Buzhen Z., Zhilong C., et al., Over-body inflammation and its prevention and cure measures, J. Medical Journal of National Defending Forces in Southwest China, 2001, 11 (1), 70-72
  • [8] Bulger E.M., May S., Brasel K.J., et al., Out-of-hospital hypertonic resuscitation following severe traumatic brain injury: a randomized controlled trial, J. Jama, 2010, 304 (13), 1455-1464[WoS]
  • [9] Xiaoqiang R., Comparative study on estimating plenty of blood transfusion for traumatic patients at early stage with four scoring standards, D. Suzhou University, 2014
  • [10] Yong L., Early-stage coagulation function changes of craniocerebral trauma patients and its impact on prognosis, Suzhou University, 2008
  • [11] Mondello S., Papa L., Buki A., et al., Neuronal and glial markers are differently associated with computed tomography findings and outcome in patients with severe traumatic brain injury: a case control study, J. Crit Care, 2011, 15(3), R156[WoS][Crossref]
  • [12] Hongsheng L., Man W., Qin S., et al., Clinical significance of the coagulation disorder dysfunction of acute severe traumatic patients, J. Traumatic surgery magazine, 2014,16 (5), 399-402
  • [13] Xueyan L., Chengxiao Z., Clinical application status and limitation of thrombelastogram, J. Medical innovation of china, 2014, (8), 127-129
  • [14] Spiotta A.M., Stiefel M.F., Gracias V.H., et al., Brain tissue oxygen-directed management and outcome in patients with severe traumatic brain injury: Clinical Article, J. Journal of Neurosurgery, 2010, 113(3), 571-580[Crossref]
  • [15] XuemeiT., Zhou Z., Coagulation function changes of patients with traumatic spinal fracture in perioperative period, J. Chongqing Medical Journal, 2007, 36 (16), 1596-1597
  • [16] Andriessen T.M.J.C., Horn J., Franschman G., et al., Epidemiology, severity classification, and outcome of moderate and severe traumatic brain injury: a prospective multicenter study, J. Journal of Neurotrauma, 2011, 28 (10), 2019-2031[WoS][Crossref]
  • [17] Cuifen p., Study on the Clinical Application of Thrombelastogram in Pregnancy Combined with Thrombocytopenia, D. Chongqing Medical University, 2010
Document Type
Publication order reference
YADDA identifier
bwmeta1.element.-psjd-doi-10_1515_med-2015-0069
Identifiers
JavaScript is turned off in your web browser. Turn it on to take full advantage of this site, then refresh the page.