PL EN


Preferences help
enabled [disable] Abstract
Number of results
Journal
2014 | 10 | 1 |
Article title

Formaldehyde may be found in cosmetic products
even when unlabelled

Content
Title variants
Languages of publication
EN
Abstracts
EN
Concomitant contact allergy to formaldehyde
and formaldehyde-releasers remains common among
patients with allergic contact dermatitis. Concentration
of free formaldehyde in cosmetic products within allowed
limits have been shown to induce dermatitis from shortterm
use on normal skin. The aim of this study was to investigate the formaldehyde
content of cosmetic products made in Lithuania.
42 samples were analysed with the chromotropic acid
(CA) method for semi-quantitative formaldehyde determination.
These included 24 leave-on (e.g., creams,
lotions) and 18 rinse-off (e.g., shampoos, soaps) products.
Formaldehyde releasers were declared on the labels of 10
products. No formaldehyde releaser was declared on the
label of the only face cream investigated, but levels of free
formaldehyde with the CA method was >40 mg/ml and
when analysed with a high-performance liquid chromatographic
method – 532 ppm. According to the EU Cosmetic
directive, if the concentration of formaldehyde is above
0.05% a cosmetic product must be labelled “contains
formaldehyde“. It could be difficult for patients allergic to
formaldehyde to avoid contact with products containing it
as its presence cannot be determined from the ingredient
labelling with certainty. The CA method is a simple and reliable method for detecting formaldehyde presence in
cosmetic products.
Publisher
Journal
Year
Volume
10
Issue
1
Physical description
Dates
received
2 - 2 - 2015
accepted
28 - 5 - 2015
online
7 - 7 - 2015
References
  • [1] de Groot A.C., Flyvholm M.A., Lensen G., Menné T., CoenraadsP.J., Formaldehyde-releasers: relationship to formaldehydecontact allergy. Contact allergy to formaldehyde and inventoryof formaldehyde-releasers, Contact Dermatitis, 2009, 61,63–85[WoS][Crossref]
  • [2] Johansen Duus J., Frosch P.J., Lepoittevin J.-P., ContactDermatitis, 5th ed., Springer, Berlin, 2011
  • [3] Fregert S., Dahlquist I., Gruvberger B., A simple method forthe detection of formaldehyde, Contact Dermatitis, 1984, 10,132–134[Crossref]
  • [4] Benassi C.A., Semenzato A., Bettero A., High-performanceliquid chromatographic determination of free formaldehyde incosmetics, J Chromatogr, 1989, 464, 387–393
  • [5] Blohm G., Formaldehyde contact dermatitis, Acta DermVenereol, 1959, 39, 450–453
  • [6] Dahlquist I., Fregert S., Gruvberger B., Reliability of thechromotropic acid method for qualitative formaldehydedetermination, Contact Dermatitis, 1980, 6, 357–358[Crossref]
  • [7] Hamburger R., Azaz E., Donbrow M., Autoxidation ofpolyethylenic non-ionic surfactants and of polyethyleneglycols, Pharm Acta Helv, 1975, 50, 10–17
  • [8] Rieger M.M., Peroxides in polyethylene glycols andpolyethylene glycol derivatives, Cosmetics Perfumery, 1975, 90,12–16
  • [9] Bergh M., Magnusson K., Nilsson J-L.G., Karlberg A-T., Contactallergenic activity of Tween 80 before and after air exposure,Contact Dermatitis, 1997, 37, 9–18[Crossref]
  • [10] Goon A., Gruvberger B., Persson L., Isaksson M., BruzeM., Presence of formaldehyde in topical corticosteroidpreparations available on the Swedish market, ContactDermatitis, 2003, 48,199–203[Crossref]
  • [11] Tegner E., Fregert F., Contamination of cosmetics withformaldehyde from tubes, Contact Dermatitis Newsletter, 1973,13, 353
  • [12] Fregert S. Contamination of chemico-technical preparationswith formaldehyde from packages, Contact Dermatitis, 1977,3,109–110[Crossref]
  • [13] de Groot A.C., White I., Flyvholm M.A., et al., Formaldehydereleasersin cosmetics: relationship to formaldehyde contactallergy. Part 1. Characterization, frequency and relevance ofsensitization, and frequency of use in cosmetics. ContactDermatitis, 2010, 62, 2-17[Crossref]
  • [14] Gruvberger B., Bruze M., Tammela M., Preservatives inmoisturizers on the Swedish market, Acta Derm Venereol,1998, 78, 52-56[Crossref]
  • [15] Rastogi S.C., A survey of formaldehyde in shampoos and skincreams on the Danish market, Contact Dermatitis 1992, 27,235-240[Crossref]
  • [16] Hauksson I., Pontén A., Isaksson M., et al., Formaldehydein skin care products and cosmetics in dermatitis patients,Contact Dermatitis, 2012, 66, 47
  • [17] Regulation (EC) No 1223/2009 of the European Parliament andof the Council of 30 November 2009 on cosmetic products, Off JEur Union, 2009, L342, 59-209
  • [18] Hauksson I., Ponten A., Gruvberger B., et al., Skin careproducts containing low concentrations of formaldehydedetected by the chromotropic acid method cannot be safelyused in formaldehyde-allergic individuals with irritant contactdermatitis. Submitted
  • [19] Flyvholm M.A., Hall B.M., Agner T., Tiedemann E., GreenhillP., Vanderweken W., Freeberg F.E., Menné T., Threshold foroccluded formaldehyde patch test in formaldehyde-sensitivepatients, Contact Dermatitis, 1997, 36, 26–33[Crossref]
  • [20] Bergh M., Magnusson K., Nilsson J.L., et al., Formation offormaldehyde and peroxides by air oxidation of high puritypolyoxyethylene surfactants, Contact Dermatitis, 1998, 39,14-20[Crossref]
  • [21] Hauksson I., Pontén A., Gruvberger B., et al., Clinically relevantcontact allergy to formaldehyde may be missed by testing withformaldehyde 1.0%, Br J Dermatol, 2011, 164, 568-572[WoS]
  • [22] Shaughnessy C.N., Malajian D., Belsito D.V., Cutaneousdelayed-type hypersensitivity in patients with atopicdermatitis: Reactivity to topical preservatives, J Am AcadDermatol, 2014, 70, 102-117[Crossref][WoS]
  • [23] Lundov M.D., Opstrup M.S., Johansen J.D., Methylisothiazolinonecontact allergy-growing epidemic, Contact Dermatitis,2013, 69, 271-275[WoS][Crossref]
  • [24] Warshaw E.M., Belsito D.V., Taylor J.S., Sasseville D., DeKovenJ.G., Zirwas M.J., et al., North American Contact DermatitisGroup patch test results: 2009 to 2010, Dermatitis, 2013, 24,50-59[Crossref]
  • [25] Isaksson M., Hauksson I., Hindsen M., et al., Methylisothiazolinonecontact allergy is rising to alarming heightsalso in southern Sweden, Acta Derm Venereol 2014,DOI:10.2340/00015555-1844[WoS][Crossref]
  • [26] Gonçalo M., Goossens A., Whilst Rome burns: the epidemic ofcontact allergy to methylisothiazolinone, Contact Dermatitis,2013, 68, 257-258 [Crossref][WoS]
Document Type
Publication order reference
YADDA identifier
bwmeta1.element.-psjd-doi-10_1515_med-2015-0047
Identifiers
JavaScript is turned off in your web browser. Turn it on to take full advantage of this site, then refresh the page.