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2014 | 1 | 1 |

Article title

Enzymatic microreactors in biocatalysis: history,
features, and future perspectives


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Microfluidic reaction devices are a very
promising technology for chemical and biochemical
processes. In microreactors, the micro dimensions,
coupled with a high surface area/volume ratio, permit
rapid heat exchange and mass transfer, resulting in higher
reaction yields and reaction rates than in conventional
reactors. Moreover, the lower energy consumption and
easier separation of products permit these systems to
have a lower environmental impact compared to macroscale,
conventional reactors. Due to these benefits, the
use of microreactors is increasing in the biocatalysis
field, both by using enzymes in solution and their
immobilized counterparts. Following an introduction
to the most common applications of microreactors in
chemical processes, a broad overview will be given of the
latest applications in biocatalytic processes performed
in microreactors with free or immobilized enzymes. In
particular, attention is given to the nature of the materials
used as a support for the enzymes and the strategies
employed for their immobilization. Mathematical and
engineering aspects concerning fluid dynamics in
microreactors were also taken into account as fundamental
factors for the optimization of these systems.








Physical description


11 - 9 - 2015
25 - 2 - 2016
3 - 3 - 2015


  • Department of Chemistry,
    University of Torino, I-10125 - Torino, Italy
  • Department of Chemical Engineering,
    University of São Paulo, 05508010 - São Paulo, SP - Brasil


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