Enhanced apatite precipitation on a
biopolymer-coated bioactive glass

• Authors: M. Araújo , M. Miola , A. Venturello , G. Baldi , J. Perez , E. Verné
• Languages of publication: EN

Abstracts

EN

In this work, sintered pellets of a silica-based
bioactive glass were dip-coated with a biocompatible
natural-derived polymer in order to investigate the influence
of the organic coating on the glass bioactivity. After
the sintering process optimization, uncoated and coated
pellets have been characterized by means of scanning
electron microscopy with energy dispersive spectroscopy
(SEM, EDS), X-ray diffraction (XRD), Fourier transform infrared
spectroscopy (FT-IR) and pH measurements, after
the immersion in a simulated body fluid (SBF). An increased
apatite forming ability and a better control of the
pH during soaking of the samples in SBF were observed in
the presence of the biopolymer. This result opens a new insight
on the simple fabrication of highly bioactive hybrid
inorganic-organic materials for medical applications.

Keywords

EN

Bioactive glass; Bioactivity; Melanin coating

• Publisher: De Gruyter Open
• Journal: Biomedical glasses
• Year: 2015
• Volume: 1
• Issue: 1

Dates

received

14 - 5 - 2015

accepted

14 - 8 - 2015

online

20 - 10 - 2015

Contributors

author

M. Araújo

• Colorobbia España S.A, Carretera CV-160, Vilafamés,
  12192, España; Ce.Ri.Col, Centro Ricerche Colorobbia, Via Pietramarina
  123, Sovigliana (FI) 50053, Italy

author

M. Miola

• Applied Science and Technology Department,
  Politecnico di Torino, Corso Duca degli Abruzzi 24, Torino,
  10129, Italy

author

A. Venturello

• Applied Science and Technology Department,
  Politecnico di Torino, Corso Duca degli Abruzzi 24, Torino,
  10129, Italy

author

G. Baldi

• Ce.Ri.Col, Centro Ricerche Colorobbia, Via Pietramarina
  123, Sovigliana (FI) 50053, Italy

author

J. Perez

• Colorobbia España S.A, Carretera CV-160, Vilafamés, 12192,
  España

author

E. Verné

• Applied Science and Technology Department,
  Politecnico di Torino, Corso Duca degli Abruzzi 24, Torino,
  10129, Italy

References

• [1] Bosetti M., Verné E., Ferraris M., Ravaglioli A., Cannas M., Invitro characterization of zirconia coated by bioactive glass, Biomaterials,2001, 22: 987–994.[Crossref]
• [2] Verné E., Fernadez-Vallés C., Vitale-Brovarone C., Spriano S.,Moisescu C., Double-layer glass-ceramic coatings on Ti6Al4Vfor dental implants, J. Eur. Ceram. Soc., 2004,24, 2699–2705.[Crossref]
• [3] Siqueira R., Zanotto E., Facile route to obtain a highly bioactiveSiO2-CaO-Na2O-P2O5 crystalline powder, Mat. Sci. Eng. C 2011,31, 1791–1799.[Crossref]
• [4] Salinas A.J., Román J., Vallet-Regí M., Oliveira J.M., Correia R.N.,Fernandes M.H., In vitro bioactivity of glass and glass-ceramicsof the 3CaO·P2O5-CaO·SiO2-CaO·MgO-2SiO2 system, Biomaterials2000, 21, 251–257.[Crossref]
• [5] Verné E., Bretcanu O., Balagna C., Bianchi C.L., Cannas M., GattiS., Vitale-Brovarone C., Early stage reactivity and in-vitro behaviourof silica-based bioactive glasses and glass-ceramics, J.Mat. Sci.: Mat. Med., 2009, 20, 75–87.[Crossref][WoS]
• [6] Magallanes-Perdomo M., Luklinska Z.B., De Azaa A.H., CarrodeguasR.G., De Azaa S., Pena P., Bone-like forming ability ofapatite–wollastonite glass ceramic, Eur. Cer. Soc. 2011, 31 (9),1549–156.[WoS]
• [7] Lefebvre L., Chevalier J., Gremillard L., Zenati R., Thollet G.,Bernache-Assolant D., Govin A., Structural transformations ofbioactive glass 45S5 with thermal treatments, Acta Materialia,2007, 55, 3305–3313.[WoS][Crossref]
• [8] Tomsia A., Saiz E., Song J., Bertozzi C., Biomimetic bonelikecomposites and novel bioactive glass coatings, Adv. Eng. Mat.2005, 7, 999–1004.
• [9] Boccaccini A., Notingher I.,Maquet V., Jérôme R., Bioresorbableand bioactive composite materials based on polylactide foamsfilled with and coated by Bioglassr for tissue engineering applications,J.Mat. Sci.: Mat. Med. 2003, 14, 443–450.[Crossref]
• [10] Bretcanu O., Misra S., Roy I., Renghini C., Fiori F., BoccacciniA., Salih V., In vitro biocompability of 45S5 Bioglassr-derivedglass-ceramic scaffolds coated with poly(3-hydroxybutyrate), J.Tissue Eng. Regen. Med. 2009, 3, 139–148.[Crossref]
• [11] Yunos D., Bretcanu O., Boccaccini A.R., Polymer-bioceramiccomposites for tissue engineering scaffolds, J. Mat. Sci. 2008,43, 4433–4442.[Crossref]
• [12] Fereshteh Z., Nooeaid P., Fathi M., Bagri A., Boccaccini A.R., Theeffect of coating type on mechanical properties and controlleddrug release of PCL/zein coated 45S5 bioactive glass scaffoldsfor bone tissue engineering, Mat. Sci.Eng. C 2015, 54, 50–60.[Crossref]
• [13] Li W., Wang H., Ding Y., Scheithauer E.C., Goudouri O.M.,Grünewald A., Detsch R., Agarwal S., Boccaccini A.R., Antibacterial45S5 Bioglassr-based scaffolds reinforced with genipincross-linked gelatin for bone tissue engineering, J. Mater.Chem. B 2015, 3, 3367–3378[WoS][Crossref]
• [14] Li W., Garmendia N., Pérez de Larraya U., Ding Y., Detsch R.,Grünewald A., Roether J.A., Schubert D.W., Boccaccini A.R.,45S5 bioactive glass-based scaffolds coated with cellulosenanowhiskers for bone tissue engineering, RSC Adv. 2014, 4,56156–56164.
• [15] Li W., Nooeaid P., Roether J.A., Schubert D.W., Boccaccini A.R.,Preparation and characterization of vancomycin releasing PHBVcoated 45S5 Bioglassr-based glass–ceramic scaffolds for bonetissue engineering, J.Europ. Cer. Soc. 2014, 34, 505–514.
• [16] Miao X., Lim W., Huang X., Chen Y., Preparation and characterizationof interpenetrating phased TCP/HA/PLGA composites,Mat. Lett. 2005, 59 (29–30), 4000–4005.
• [17] Huang X., Miao X., Novel Porous Hydroxyapatite prepared bycombining H2O2 foaming with PU sponge and modified withPLGA and bioactive glass, J. Biomat. Appl. 2007, 21, 351–374.[Crossref]
• [18] Wu C., Ramaswamy Y., Boughton P., Zreiqat H., Improvementof mechanical and biological properties of porous CaSiO3 scaffoldsby poly(D,L-lactic acid) modification, Acta Biomaterialia2008, 5, 343–353.[Crossref][WoS]
• [19] Kim H., Knowles J., Kim H.E., Development of hydroxyapatitebone scaffold for controlled drug release via poly(epsiloncaprolactone)and hydroxyapatite hybrid coatings, J. Biomed.Mat. Res. B: Appl. Biomater. 2004, 70, 240–249.[Crossref]
• [20] Krajewski A., Ravaglioli A., Tinti A., Taddei P.,Mazzocchi M., FagnanoC., Fini M., Comparison between the in vitro surface transformationsof AP40 and RKKP bioactive glasses, J. Mat. Sci.:Mat. Med. 2005, 16, 119–128.[Crossref]
• [21] Verné E., Ferraris M., Ventrella A., Paracchini L., Krajewski A.,Ravaglioli A., Sintering and plasma spray deposition of bioactiveglass-matrix composites for medical applications, J. Eur. Ceram.Soc. 1998, 18, 363–372.[Crossref]
• [22] Couto D., Hong Z., Mano J., Development of bioactive andbiodegradable chitosan-based injectable systems containingbioactive glass nanoparticles, Acta Biomaterialia 2009, 5, 115–123.[WoS][Crossref]
• [23] Araujo M., Xavier J.R., Nunes C.D., Vaz P.D., Humanes M., Marinesponge melanin: a new source of an old biopolymer, Struct.Chem. 2012, 23, 115–122.[Crossref][WoS]
• [24] Araújo M., Viveiros R., Correia T., Correia I., Bonifácio V.,Casimiro T., Aguiar-Ricardo A., Natural melanin: A potential pHresponsivedrug release device, Int. J. of Pharm. 2014, 469, 140–145.[WoS][Crossref]
• [25] Riley P.A., Molecules in focus – Melanin, Int. J. Biochem. CellBiology, 1997, 29, 1235–1239.[Crossref]
• [26] D’Ischia M., Napolitano A., Pezzella A., Meredith P., Sarna T.,Chemical and structural diversity in eumelanins: unexploredbio-optoelectronic materials, Angew. Chem. Int. Ed. 2009, 48,3914–3921.[WoS][Crossref]
• [27] Araújoa M., Miola M., Bertone E., Baldi G., Pereza J., Verné E.,On the mechanism of apatite-induced precipitation on 45S5glasspellets coated with a natural-derived polymer, App. Surf.Sci. 2015, 353, 137–149.[WoS][Crossref]
• [28] Kokubo T., Takadama H., How useful is SBF in predicting in vivobone bioactivity?, Biomaterials 2006, 27, 2907–2915.[Crossref]
• [29] Lebecq I., Désanglois F., Leriche A., Follet-Houttemane C., Compositionaldependence on the in vitro bioactivity of invert orconventional bioglasses in the Si-Ca-Na-P system, J. Biomed.Res. A 2007, 83A, 156–168.[WoS]
• [30] Radev L., Hristov V., Michailova I., Samuneva B., Sol-gel bioactiveglass-ceramics Part II: Glass-ceramics in the CaO-SiO2-P2O5-MgO system, Centr. Eur. J. Chem. 2009, 7, 322–327.[Crossref][WoS]
• [31] Kansal I., Goel A., Tulyaganov D.U., Pascual M.J., Lee H., KimH.W., Ferreira J.M.F., Diopside (CaO·MgO·2SiO2)-fluorapatite(9CaO·3P2O5·CaF2) glass-ceramics: potential materials forbone tissue engineering, J. Mat. Chem. 2011, 21, 16247–16256.[Crossref]
• [32] Stan G.E., Popa A.C., Galca A.C., Aldica G., Ferreira J.M.F.,Strong bonding between sputtered bioglass ceramic films andTi-substrate implants induced by atomic inter-diffusion postdepositionheat-treatments, Appl. Surf. Sci. 2013, 280, 530–538.[WoS][Crossref]
• [33] Liu X., Ding C., Chu P., Mechanism of apatite formation on wollastonitecoatings in simulated body fluids, Biomaterials 2004,25, 1755–1761.[Crossref]
• [34] Baghbani F., Moztarzadeh F., Leila H., Mozafari M., Synthesis,characterization and evaluation of bioactivity and antibacterialactivity of quinary glass system (SiO2-CaO-P2O5-MgO-ZnO): Invitro study, Bull. Mat. Sci. 2013, 36, 1339–1346.[WoS][Crossref]
• [35] Rahaman M.N., Day D.E., Bal B.S., Fu Q., Jung S.B., BonewaldL.F., Tomsia A.P., Bioactive glass in tissue engineering, Acta Biomaterialia2011, 7, 2355–2373.[WoS][Crossref]

Identifiers

DOI

10.1515/bglass-2015-0011