New feats of alkene and alkyne asymmetric
hydroamination catalyzed by copper and rhodium
hydrides

• Authors: Alessandro Dondoni
• Languages of publication: EN

Abstracts

EN

Hydroamination of unsaturated carbon-carbon
bonds is a useful C-N bond forming reaction as it leads
to products (amines, imines, enamines) of high synthetic
value. While the hydroamination of terminal alkenes and
alkynes under metal catalysis has been widely developed,
the corresponding reactions with internal substrates
remain a challenge. Two recent studies by Buchwald and
by Dong which focus on enantioselective hydroamination
of internal alkenes and alkynes respectively are of
significant importance. [43,44] The results reported
broaden the scope of hydroamination as a useful C-N
bond forming process and allow acess to chiral amines
which are difficult to synthesize by other methods.

Keywords

EN

Amines; copper; rhodium; asymmetric; hydroamination

• Publisher: De Gruyter Open
• Journal: Asymmetric Catalysis
• Year: 2015
• Volume: 2
• Issue: 1

Dates

accepted

10 - 11 - 2015

received

13 - 10 - 2015

online

3 - 2 - 2016

Contributors

author

Alessandro Dondoni

• Interdisciplinary
  Center for the Study of Inflammation, University of Ferrara, Via L.
  Borsari 46, I-44121 Ferrara (Italy)

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Identifiers

DOI

10.1515/asorg-2015-0006