Mimicking catalase and catecholase enzymes by copper(II)-containing complexes

• Authors: István Szilágyi , László. Horváth , Imre Labádi , Klara Hernadi , István Pálinkó , Tamás Kiss
• Languages of publication: EN

Abstracts

EN

An imidazolate-bridged copper(II)-zinc(II) complex (Cu(II)-diethylenetriamino-μ-imidazolato-Zn(II)-tris(2-aminoethyl)amine perchlorate (denoted as “Cu,Zn complex”) and a simple copper(II) complex (Cu(II)-tris(2-aminoethyl) amine chloride (“Cu-tren”) were prepared and immobilised on silica gel (by hydrogen or covalent bonds) and montmorillonite (by ion exchange). The immobilised substances were characterised by FT-IR spectroscopy and their thermal characteristics were also studied. The obtained materials were tested in two probe reactions: catalytic oxidation of 3,5-di-tert-butyl catechol (DTBC) (catecholase activity) and the decomposition of hydrogen peroxide (catalase activity). It was found that the catecholase activity of the Cu,Zn complex increased considerably upon immobilization on silica gel via hydrogen bonds and intercalation by ion exchange among the layers of montmorillonite. The imidazolate-bridged copper(II)-zinc(II) complex and its immobilised versions were inactive in hydrogen peroxide decomposition. The Cu(II)-tris(2-aminoethyl)amine chloride complex displayed good catalase activity; however, immobilisation could not improve it.

Keywords

EN

Copper(II) complexes; immobilisation; enzyme mimics; catalase activity; catecholase activity

• Publisher: De Gruyter Open
• Journal: Open Chemistry
• Year: 2006
• Volume: 4
• Issue: 1
• Pages: 118-134

Dates

published

1 - 3 - 2006

online

1 - 3 - 2006

Contributors

author

István Szilágyi

• Department of Inorganic and Analytical Chemistry, University of Szeged, Dóm tér 7, H-6720, Szeged, Hungary

author

László. Horváth

• Department of Inorganic and Analytical Chemistry, University of Szeged, Dóm tér 7, H-6720, Szeged, Hungary

author

Imre Labádi

• Department of Inorganic and Analytical Chemistry, University of Szeged, Dóm tér 7, H-6720, Szeged, Hungary

author

Klara Hernadi

• Department of Applied and Environmental Chemistry, University of Szeged, Rerrich B. tér 1, H-6720, Szeged, Hungary

author

István Pálinkó

• Department of Organic Chemistry, University of Szeged, Dóm tér 8, H-6720, Szeged, Hungary

author

Tamás Kiss

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Identifiers

DOI

10.1007/s11532-005-0009-6